NAUT · 10-Q · 2026Q1 · Full report

Macroeconomic Factors Impact

Nautilus Biotechnology, Inc. · 2026-04-28 · Importance 13 · Surprise 6

Nautilus states that its business may be affected by a range of global and national events, explicitly citing extreme weather, economic uncertainty, increased tariffs, inflation, changing interest rates, potential financial institution failures, and geopolitical conflicts such as those in Eastern Europe and the Middle East. The company reports it has experienced supply disruptions in the past (including chip manufacturer closures that led to extended lead times and reagent availability issues) and is conducting ongoing contingency planning with partners to reduce interruption risk. Management warns these events could affect development timelines, third-party manufacturers, regulatory authorities and key personnel, and that the ultimate impact on operations, expenditures and capital needs is uncertain. Nautilus indicates it is actively monitoring developments and may take operational actions as warranted by federal, state or local authorities or business needs.