VRTX · 8-K · 20261102PR000287

FX / Currency Impact

VERTEX PHARMACEUTICALS INC / MA · 2026-11-02 · Importance 43 · Surprise 32

Vertex said its full-year 2026 total revenue guidance includes an approximately 150-basis-point year-over-year benefit from foreign exchange rate changes. This estimate is net of Vertex’s foreign-exchange hedging program. Applied to the company’s $13.15 billion–$13.25 billion revenue guidance, the stated benefit represents an approximate $200 million contribution, exceeding the materiality threshold.

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