VRTX · 10-Q · 2026Q2 · Full report

Supply Chain Constraints

VERTEX PHARMACEUTICALS INC / MA · 2026-08-04 · Importance 29 · Surprise 24

Vertex relies on a global network of third-party manufacturers and distributors, including some suppliers in China, alongside internal capabilities. The company is establishing supply chains for newly approved products and adapting existing networks to add formulations or increase production scale as demand develops. Cell and genetic therapies require more complex processes than small-molecule drugs and additional systems, equipment, facilities and specialized expertise, increasing supply-chain execution requirements for CASGEVY and the pipeline.